Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Estimating risk curves for first-degree relatives of patients with Alzheimer's disease: the REVEAL study.

Genetics in medicine : official journal of the American College of Medical Genetics - 1 Jan 2000

Cupples L Adrienne, Farrer Lindsay A, Sadovnick A Dessa, Relkin Norman, Whitehouse Peter, Green Robert C

Abstract excerpt

PURPOSE: The REVEAL study is a randomized, controlled study of the psychological and behavioral impact of APOE disclosure in a risk assessment protocol provided to first degree relatives of patients with Alzheimer's disease. The protocol presents risk information as cumulative incidence curves. This article describes how these curves were estimated. METHODS: Curves were calculated using Bayes' rule to compute the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alzheimer Disease
Share to Apolipoprotein E3

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Apolipoprotein E4

Share to Apolipoproteins E

Share to Family Health

Share to Genetic Counseling

Share to Randomized Controlled Trials as Topic

Source

Identifiers

PMID: 15266206
DOI: 10.1097/01.gim.0000132679.92238.58

Genes

APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Estimating risk curves for first-degree relatives of patients with Alzheimer's disease: the REVEAL study.PMID 15266206Read ↗

Genetic risk assessment for adult children of people with Alzheimer's disease: the Risk Evaluation and Education for Alzheimer's Disease (REVEAL) study.Semantic proximity Read ↗

Health behavior changes after genetic risk assessment for Alzheimer disease: The REVEAL Study.Semantic proximity Read ↗

Disclosure of APOE genotype for risk of Alzheimer's disease.Semantic proximity Read ↗

Genetic susceptibility testing versus family history-based risk assessment: Impact on perceived risk of Alzheimer disease.Semantic proximity Read ↗

Recall of disclosed apolipoprotein E genotype and lifetime risk estimate for Alzheimer's disease: the REVEAL Study.Semantic proximity Read ↗

Safety and Tolerability of APOE Genotyping and Disclosure in Cognitively Normal Volunteers From the Butler Alzheimer's Prevention Registry.Semantic proximity Read ↗

Disclosing Pleiotropic Effects During Genetic Risk Assessment for Alzheimer Disease: A Randomized Trial.Semantic proximity Read ↗

A randomized controlled trial of disclosing genetic risk information for Alzheimer disease via telephone.Semantic proximity Read ↗

Disclosure of APOE Genotype for Risk of Alzheimer's DiseaseSemantic proximity Read ↗

Using Alzheimer's disease as a model for genetic risk disclosure: implications for personal genomics.Semantic proximity Read ↗

Incorporating ethnicity into genetic risk assessment for Alzheimer disease: the REVEAL study experience.Semantic proximity Read ↗

Effectiveness of a condensed protocol for disclosing APOE genotype and providing risk education for Alzheimer disease.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.