Article
Genetic susceptibility testing versus family history-based risk assessment: Impact on perceived risk of Alzheimer disease.
Genetics in medicine : official journal of the American College of Medical Genetics - 1 Jan 2005
LaRusse Susan, Roberts J Scott, Marteau Theresa M, Katzen Heather, Linnenbringer Erin L, Barber Melissa, Whitehouse Peter, Quaid Kimberly, Brown Tamsen, Green Robert C, Relkin Norman R
Abstract excerpt
PURPOSE: We examined how an Alzheimer disease (AD) family history assessment as compared to a risk assessment incorporating the absence of a disease-associated susceptibility allele affected risk perception among adult children with a family history of AD. METHODS: The REVEAL study is a clinical trial in which adult children of patients with AD were randomized to receive a risk assessment based upon family...
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