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Article

Crystal structure of leucotoxin S component: new insight into the Staphylococcal beta-barrel pore-forming toxins.

The Journal of biological chemistry - 24 Sept 2004

Guillet Valérie, Roblin Pierre, Werner Sandra, Coraiola Manuela, Menestrina Gianfranco, Monteil Henri, Prévost Gilles, Mourey Lionel

Abstract excerpt

Staphylococcal leucocidins and gamma-hemolysins (leucotoxins) are bi-component toxins that form lytic transmembrane pores. Their cytotoxic activities require the synergistic association of a class S component and a class F component, produced as water-soluble monomers that form hetero-oligomeric membrane-associated complexes. Strains that produce the Panton-Valentine leucocidin are clinically associated with...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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PMID: 15262988
DOI: 10.1074/jbc.M406904200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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