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Article

Improved techniques for the identification of pseudogenes.

Bioinformatics (Oxford, England) - 4 Aug 2004

Coin L, Durbin R

Abstract excerpt

MOTIVATION: Pseudogenes are the remnants of genomic sequences of genes which are no longer functional. They are frequent in most eukaryotic genomes, and an important resource for comparative genomics. However, pseudogenes are often mis-annotated as functional genes in sequence databases. Current methods for identifying pseudogenes include methods which rely on the presence of stop codons and frameshifts, as well...

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PMID: 15262786
DOI: 10.1093/bioinformatics/bth942

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