Article
The ambiguous boundary between genes and pseudogenes: the dead rise up, or do they?
Trends in genetics : TIG - 1 May 2007
Zheng Deyou, Gerstein Mark B
Abstract excerpt
Pseudogenes have long been considered to be 'dead', nonfunctional by-products of genome evolution. However, several lines of evidence now show that some pseudogenes are transcriptionally 'alive', and a few might even have biochemical roles. Therefore, the boundary between genes (often considered to be 'living') and pseudogenes (often considered to be 'dead') might be ambiguous and difficult to define. Here, we...
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