Persistence of HIV-1 drug resistance mutations and emergence during antiretroviral treatment interruption: considerations from a clinical case.

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Article

Persistence of HIV-1 drug resistance mutations and emergence during antiretroviral treatment interruption: considerations from a clinical case.

Medical science monitor : international medical journal of experimental and clinical research - 1 Apr 2003

Torti Carlo, Moretti Francesca, Uccelli Maria C, Tirelli Valeria, Quiros-Roldan Eugenia, Gargiulo Franco, Carosi Giampiero

Abstract excerpt

BACKGROUND: HIV drug resistance (HDR) represents a crucial problem in antiretroviral therapy today. HDR mutations can accumulate, persist in the proviral genome and re-emerge, promoting further failure of rescue regimens. Resistance testing on the proviral genome has been suggested in order to detect the presence of archived resistance mutations and to guide drug prescription. CASE REPORT: We report the...

Topics

Anti-HIV Agents
Antiretroviral Therapy, Highly Active
DNA, Viral
Drug Administration Schedule
Drug Resistance, Multiple, Viral
Drug Resistance, Viral
Drug Therapy, Combination
Female
Genotype

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

HIV Infections

HIV-1

Humans

Middle Aged

Mutation

Time Factors

Treatment Failure

Source

Open in PubMed

Identifiers

PMID: 12709675

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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