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Article

Dissociation of cardiomyocyte apoptosis and dedifferentiation in infarct border zones

1 Jun 2002

Abstract excerpt

AIMS: Cardiomyocyte apoptosis is known to occur in infarct border zones, where cardiomyocyte dedifferentiation, as seen in hibernating myocardium, can also be observed. The aim of the study is to determine whether dedifferentiated cardiomyocytes represent a population of cells stably surviving or undergoing apoptosis. METHODS AND RESULTS: Microinfarctions were induced in sheep (n=8) by intracoronary injection of...

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PMID: 12042006
DOI: 10.1053/euhj.2001.2963

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