Article
rexAB mutants in Streptococcus pneumoniae.
Microbiology (Reading, England) - 1 Jul 2004
Halpern David, Gruss Alexandra, Claverys Jean-Pierre, Karoui Meriem El
Abstract excerpt
Streptococcus pneumoniae is a human pathogen that is naturally transformable. In this study a major component of the homologous recombination pathway, the RexAB exonuclease/helicase, was characterized. rexA and rexB insertional mutants were constructed using mariner mutagenesis and found to have identical phenotypes. Both rexAB mutants displayed poor cell viability, reduced double-strand exonuclease activity, UV...
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