Article
Case-control study of genotypes in multiple chemical sensitivity: CYP2D6, NAT1, NAT2, PON1, PON2 and MTHFR.
International journal of epidemiology - 1 Oct 2004
McKeown-Eyssen Gail, Baines Cornelia, Cole David E C, Riley Nicole, Tyndale Rachel F, Marshall Lynn, Jazmaji Vartouhi
Abstract excerpt
BACKGROUND: Impaired metabolism of toxic chemicals is a postulated mechanism underlying multiple chemical sensitivity (MCS). Because genetic variation alters the rate of chemical metabolism, this study was designed to determine if MCS cases differed from controls for genetic polymorphisms in drug-metabolizing enzymes. METHODS: Female Caucasian participants (203 cases and 162 controls) were drawn from a larger...
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