Article
Pharmacogenetics: detecting sensitive populations.
Environmental health perspectives - 1 Dec 1994
Shields P G
Abstract excerpt
Risk assessment models strive to predict risks to humans from toxic agents. Safety factors and assumptions are incorporated into these models to allow a margin of error. In the case of cancer, substantial evidence shows that the carcinogenic process is a multistage process driven by the interacti...
Topics
- Carcinogens
- Cytochrome P-450 Enzyme System
- Dose-Response Relationship, Drug
- Genetic Predisposition to Disease
- Genetic Testing
- Humans
- Models, Genetic
- Neoplasms
- Pharmacogenetics
- Polymorphism, Restriction Fragment Length
- Risk Assessment
- Risk Factors