Article
Sequence variations in subjects with self-reported multiple chemical sensitivity (sMCS): a case-control study.
Journal of toxicology and environmental health. Part A - 1 Jan 2008
Wiesmüller Gerhard A, Niggemann Hiltrud, Weissbach Wibke, Riley Felix, Maarouf Zackaria, Dott Wolfgang, Kunert Hanns-Jürgen, Zerres Klaus, Eggermann Thomas, Blömeke Brunhilde
Abstract excerpt
Polymorphisms in several genes contribute to interindividual differences in the metabolism of xenobiotics, and may lead to toxicity and disease. The balance between activation and/or detoxification processes may influence an individual's susceptibility to disease. One postulated mechanism underlying multiple chemical sensitivity (MCS) is based on increased metabolism of xenobiotics. The aim of the present study...
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