Article
Mapping phenotypic landscapes using DNA micro-arrays.
Metabolic engineering - 1 Jul 2004
Lynch Michael D, Gill Ryan T, Stephanopoulos Gregory
Abstract excerpt
Inverse metabolic engineering is a useful approach for engineering phenotypes in biological systems. The overarching objective of this approach is to combine the power of evolutionary engineering approaches with the precision of constructive metabolic engineering strategies. Often the difficulty in this approach is elucidating the genetic basis of the phenotypes that emerge as a result of evolutionary mechanisms....
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