Article
Enabling inverse metabolic engineering through genomics.
Current opinion in biotechnology - 1 Oct 2003
Gill Ryan T
Abstract excerpt
Inverse metabolic engineering (IME) is a powerful framework for engineering cellular phenotypes. Progress in this field has been limited by a lack of comprehensive methods for efficiently identifying the genetic basis of relevant phenotypes. Advances in genomics technologies, including DNA microarrays and gene sequencing, have dramatically improved our ability to relate changes in phenotype with associated...
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