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Article

Implications of cytokeratin 8/18 filament formation in stratified epithelial cells: induction of transformed phenotype.

International journal of cancer - 20 Sept 2004

Raul Ujwala, Sawant Sharada, Dange Prerana, Kalraiya Rajiv, Ingle Arvind, Vaidya Milind

Abstract excerpt

The cytokeratin (CK) pair 8 and 18 is normally expressed in all simple epithelia. This pair is not normally seen in stratified epithelial cells. Squamous cell carcinomas derived from stratified epithelia show anomalous expression of this CK pair. It is not known whether CKs 8 and 18 in any way contribute to the malignant phenotype of these cells. We used an immortalised, nontransformed human foetal buccal mucosa...

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Identifiers

PMID: 15252834
DOI: 10.1002/ijc.20349

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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