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Article

O-GlcNAcylation determines the solubility, filament organization, and stability of keratins 8 and 18.

The Journal of biological chemistry - 29 Oct 2010

Srikanth Budnar, Vaidya Milind M, Kalraiya Rajiv D

Abstract excerpt

Keratins 8 and 18 (K8/18) are intermediate filament proteins expressed specifically in simple epithelial tissues. Dynamic equilibrium of these phosphoglycoproteins in the soluble and filament pool is an important determinant of their cellular functions, and it is known to be regulated by site-specific phosphorylation. However, little is known about the role of dynamic O-GlcNAcylation on this keratin pair. Here,...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 20729549
DOI: 10.1074/jbc.M109.098996
PMCID: PMC2962505

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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