Article
Lineage-specific gene duplication and loss in human and great ape evolution.
PLoS biology - 1 Jul 2004
Fortna Andrew, Kim Young, MacLaren Erik, Marshall Kriste, Hahn Gretchen, Meltesen Lynne, Brenton Matthew, Hink Raquel, Burgers Sonya, Hernandez-Boussard Tina, Karimpour-Fard Anis, Glueck Deborah, McGavran Loris, Berry Rebecca, Pollack Jonathan, Sikela James M
Abstract excerpt
Given that gene duplication is a major driving force of evolutionary change and the key mechanism underlying the emergence of new genes and biological processes, this study sought to use a novel genome-wide approach to identify genes that have undergone lineage-specific duplications or contractions among several hominoid lineages. Interspecies cDNA array-based comparative genomic hybridization was used to...
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