Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The ATC1 gene encodes a cell wall-linked acid trehalase required for growth on trehalose in Candida albicans.

The Journal of biological chemistry - 24 Sept 2004

Pedreño Yolanda, Maicas Sergi, Argüelles Juan-Carlos, Sentandreu Rafael, Valentin Eulogio

Abstract excerpt

After screening a Candida albicans genome data base, the product of an open reading frame (IPF 19760/CA2574) with 41% identity to Saccharomyces cerevisiae vacuolar acid trehalase (Ath1p) was identified and named Atc1p. The deduced amino acid sequence shows that Atc1p contains an N-terminal hydrophobic signal peptide and 20 potential sites for N-glycosylation. C. albicans homozygous mutants that lack acid...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Candida albicans
Share to Carbon

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Cell-Free System

Share to Cell Wall

Share to Glucose

Share to Phosphoproteins

Share to Protein Biosynthesis

Share to Trehalose

Source

Identifiers

PMID: 15252058
DOI: 10.1074/jbc.M400216200

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The ATC1 gene encodes a cell wall-linked acid trehalase required for growth on trehalose in Candida albicans.PMID 15252058Read ↗

Disruption of the Candida albicans ATC1 gene encoding a cell-linked acid trehalase decreases hypha formation and infectivity without affecting resistance to oxidative stressSemantic proximity Read ↗

Evaluating cellular roles and phenotypes associated with trehalose degradation genes in Saccharomyces cerevisiae.Semantic proximity Read ↗

Trehalose is an important mediator of Cap1p oxidative stress response in Candida albicans.Semantic proximity Read ↗

Structural and In Vivo Studies on Trehalose-6-Phosphate Synthase from Pathogenic Fungi Provide Insights into Its Catalytic Mechanism, Biological Necessity, and Potential for Novel Antifungal Drug Design.Semantic proximity Read ↗

Expansion, functional diversification and gene fusion events in the Ato protein familySemantic proximity Read ↗

Lack of Functional Trehalase Activity in Candida Parapsilosis Increases Susceptibility to ItraconazoleSemantic proximity Read ↗

Disruption of the <i>Candida albicans TPS2</i> Gene Encoding Trehalose-6-Phosphate Phosphatase Decreases Infectivity without Affecting Hypha FormationSemantic proximity Read ↗

Global transcriptional profiling of Candida albicans cwt1 null mutant.Semantic proximity Read ↗

New insights into trehalose metabolism by Saccharomyces cerevisiae: NTH2 encodes a functional cytosolic trehalase, and deletion of TPS1 reveals Ath1p-dependent trehalose mobilization.Semantic proximity Read ↗

Characterization of AGT1 encoding a general alpha-glucoside transporter from Saccharomyces.Semantic proximity Read ↗

Tcc1p, a novel protein containing the tetratricopeptide repeat motif, interacts with Tup1p to regulate morphological transition and virulence in Candida albicans.Semantic proximity Read ↗

Disruption of the yeast ATH1 gene confers better survival after dehydration, freezing, and ethanol shock: potential commercial applications.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.