Article
Disruption of the yeast ATH1 gene confers better survival after dehydration, freezing, and ethanol shock: potential commercial applications.
Applied and environmental microbiology - 1 May 1996
Kim J, Alizadeh P, Harding T, Hefner-Gravink A, Klionsky D J
Abstract excerpt
The accumulation of trehalose is a critical determinant of stress resistance in the yeast Saccharomyces cerevisiae. We have constructed a yeast strain in which the activity of the trehalose-hydrolyzing enzyme, acid trehalase (ATH), has been abolished. Loss of ATH activity was accomplished by disr...
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