Article
Limits of HLA mismatching in unrelated hematopoietic cell transplantation.
Blood - 1 Nov 2004
Petersdorf Effie W, Anasetti Claudio, Martin Paul J, Gooley Ted, Radich Jerald, Malkki Mari, Woolfrey Ann, Smith Anajane, Mickelson Eric, Hansen John A
Abstract excerpt
HLA matching between the donor and recipient improves the success of unrelated hematopoietic cell transplantation (HCT). Matched donors are available for only a minority of patients. Further information is needed to evaluate the limits of HLA mismatching. We examined the association of mortality with HLA-A, -B, -C, -DRB1, and -DQB1 mismatching in 948 patients who received a T-replete unrelated HCT for treatment...
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