Article
Androgen sensitivity and gene expression in ras + myc-induced mouse prostate carcinomas.
The Journal of steroid biochemistry and molecular biology - 1 Sept 1992
Thompson T C, Egawa S, Kadmon D, Miller G J, Timme T L, Scardino P T, Park S H
Abstract excerpt
We established an androgen-sensitive cell line (BR31-5) from a ras + myc-induced mouse prostate carcinoma and used this cell line together with a previously reported transplantable androgen-independent mouse prostate carcinoma to investigate patterns of expression for apoptosis-related genes in an androgen-deprived environment. Single cell suspensions derived from the BR31-5 cell line were inoculated into the...
Topics
- Androgens
- Animals
- Cell Death
- Cell Division
- Cell Line
- Disease Models, Animal
- Gene Expression Regulation, Neoplastic
- Genes, myc
- Genes, ras
- Kinetics
- Male
