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Article

Testosterone regulates cell proliferation in aggressive fibromatosis (desmoid tumour).

British journal of cancer - 26 Apr 2011

Hong H, Nadesan P, Poon R, Alman B A

Abstract excerpt

BACKGROUND: Aggressive fibromatosis (desmoid tumour) is a locally invasive tumour caused by mutations resulting in β-catenin protein stabilisation. Apc1638N mice are predisposed to developing aggressive fibromatosis tumours, and male mice develop greater numbers of tumours than female mice, suggesting a role for androgens in this tumour type. METHODS: Human aggressive fibromatosis tumours were examined for the...

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Identifiers

PMID: 21468052
DOI: 10.1038/bjc.2011.107
PMCID: PMC3101926

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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