Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

TabBO: a model reflecting common molecular features of androgen-independent prostate cancer.

Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Mar 2000

Navone N M, Rodriquez-Vargas M C, Benedict W F, Troncoso P, McDonnell T J, Zhou J H, Luthra R, Logothetis C J

Abstract excerpt

We established two human prostate cancer cell lines, MDA PCa 2a and MDA PCa 2b, the TabBO model system, that reflect common features of human androgen-independent prostate cancer that are not present in other model systems: bone origin, prostate-specific antigen production, androgen receptor expression, and androgen sensitivity. We therefore hypothesized that molecular pathways in our model system reflect common...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Androgens
Share to bcl-2-Associated X Protein

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Cyclin-Dependent Kinase Inhibitor p21

Share to Cyclins

Share to Neoplasm Transplantation

Share to Proto-Oncogene Proteins c-bcl-2

Share to Retinoblastoma Protein

Share to Transplantation, Heterologous

Source

Identifiers

PMID: 10741751

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

TabBO: a model reflecting common molecular features of androgen-independent prostate cancer.PMID 10741751Read ↗

CELL LINES USED IN PROSTATE CANCER RESEARCH: A COMPENDIUM OF OLD AND NEW LINES—PART 2Semantic proximity Read ↗

CELL LINES USED IN PROSTATE CANCER RESEARCH: A COMPENDIUM OF OLD AND NEW LINES—PART 1Semantic proximity Read ↗

Apoptosis in prostate cancer: progressive and therapeutic implications (Review).Semantic proximity Read ↗

Signaling Pathways That Control Apoptosis in Prostate CancerSemantic proximity Read ↗

Androgen-independent growth of LNCaP prostate cancer cells is mediated by gain-of-function mutant p53.Semantic proximity Read ↗

Molecular advances in prostate cancer.Semantic proximity Read ↗

FGFR1 and WT1 are markers of human prostate cancer progressionSemantic proximity Read ↗

Cell-resolved high-dimensional imaging analysis, therapeutic modeling, and a Phase Ib clinical study establish BCL-2 as a target across heterogeneous CRPC subtypesSemantic proximity Read ↗

Sabutoclax, a Mcl-1 Antagonist, Inhibits Tumorigenesis in Transgenic Mouse and Human Xenograft Models of Prostate CancerSemantic proximity Read ↗

The development of androgen-independent prostate cancer.Semantic proximity Read ↗

Androgen-regulated and highly tumorigenic human prostate cancer cell line established from a transplantable primary CWR22 tumor.Semantic proximity Read ↗

Hypoxia selects for androgen independent LNCaP cells with a more malignant geno- and phenotype.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.