Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Apolipoprotein E genotype and age at menopause.

Annals of the New York Academy of Sciences - 1 Jun 2004

Koochmeshgi Jalal, Hosseini-Mazinani Seyed Mehdi, Morteza Seifati Seyed, Hosein-Pur-Nobari Nasrin, Teimoori-Toolabi Ladan

Abstract excerpt

We tested the hypothesis that there is a connection between apolipoprotein E (APOE) genotype and age at menopause. A sample of women aged between 50 and 60 years who had reached natural menopause was studied. Survival analysis of data showed a significant relationship between APOE genotype and age at menopause, carriers of the APOE4 allele reaching menopause at an earlier age. Our findings can have a bearing on...

Topics

Age Factors
Alleles
Apolipoproteins E
Female
Genotype
Humans
Menopause
Middle Aged
Polymorphism, Genetic

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 15247087
DOI: 10.1196/annals.1297.105

Genes

APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Apolipoprotein E genotype and age at menopause.PMID 15247087Read ↗

A polymorphism of apolipoprotein E (APOE) gene is associated with age at natural menopause in Caucasian females.Semantic proximity Read ↗

ApoE genotypes are associated with age at natural menopause in Chinese females.Semantic proximity Read ↗

Shared Genetics Between Age at Menopause, Early Menopause, POI and Other TraitsSemantic proximity Read ↗

Apolipoprotein E gene determines serum testosterone and dehydroepiandrosterone levels in postmenopausal women.Semantic proximity Read ↗

An Appraisal of the Role of Previously Reported Risk Factors in the Age at Menopause Using Mendelian RandomizationSemantic proximity Read ↗

Factor V Leiden mutation accelerates the onset of natural menopause.Semantic proximity Read ↗

Progress in genome-wide association studies of age at natural menopauseSemantic proximity Read ↗

Predictive factors for age at menopause in Caucasian females.Semantic proximity Read ↗

Accelerated cell aging in female APOE-ε4 carriers: implications for hormone therapy use.Semantic proximity Read ↗

Apolipoprotein E (ApoE) polymorphism is related to differences in potential fertility in women: a case of antagonistic pleiotropy?Semantic proximity Read ↗

Apolipoprotein E Polymorphism and Reproductive Patterns Among Postreproductive Women.Semantic proximity Read ↗

Apolipoprotein E genotype and response of lipid levels to postmenopausal estrogen use.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.