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Article

Genetic correction of mitochondrial diseases: using the natural migration of mitochondrial genes to the nucleus in chlorophyte algae as a model system.

Annals of the New York Academy of Sciences - 1 Jun 2004

González-Halphen Diego, Funes Soledad, Pérez-Martínez Xochitl, Reyes-Prieto Adrián, Claros M Gonzalo, Davidson Edgar, King Michael P

Abstract excerpt

Mitochondrial diseases display great diversity in clinical symptoms and biochemical characteristics. Although mtDNA mutations have been identified in many patients, there are currently no effective treatments. A number of human diseases result from mutations in mtDNA-encoded proteins, a group of proteins that are hydrophobic and have multiple membrane-spanning regions. One method that has great potential for...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 15247021
DOI: 10.1196/annals.1297.039

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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