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Article

The prion gene complex encoding PrP(C) and Doppel: insights from mutational analysis.

Gene - 5 Sept 2001

Mastrangelo P, Westaway D

Abstract excerpt

The prion protein gene, Prnp, encodes PrP(Sc), the major structural component of prions, infectious pathogens causing a number of disorders including scrapie and bovine spongiform encephalopathy (or BSE). Missense mutations in the human Prnp gene cause inherited prion diseases such as familial Creutzfeldt-Jakob disease. In uninfected animals Prnp encodes a glycophosphatidylinositol (GPI)-anchored protein denoted...

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Identifiers

PMID: 11574147
DOI: 10.1016/s0378-1119(01)00627-8

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GPI

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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