Article
Lack of association between the -2518G/A polymorphism of the MCP-1 gene and ischaemic heart disease: a family-based investigation.
Tissue antigens - 1 Aug 2004
McGlinchey P G, Spence M S, Patterson C C, Allen A R, Murphy G, Belton C, McKeown P P
Abstract excerpt
Using two recently described family-based tests of association, the possible role of the functional -2518G/A polymorphism in the promoter region of the monocyte chemoattractant protein-1 (MCP-1) gene in the susceptibility to ischaemic heart disease (IHD) was investigated in a well-defined Irish population. One thousand and twelve individuals from 386 families with at least one member prematurely affected with IHD...
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