Article
[Hereditary non polyposis colon cancer--basic principle and ethical considerations].
Revue medicale suisse - 30 Nov 2005
Bouzourene Hanifa, Monnerat Christian
Abstract excerpt
HNPCC is a hereditary cancer syndrome of several organs but more particularly the colon and the uterus. It is characterized by microsatellite instability (MSI) related to mutations of DNA mismatch repair (MMR) genes. The role of the pathologist in the detection of colorectal cancer with MSI phenotype is important. Among the available tests to detect MSI, immunohistochemistry appears being a sensitive, specific...
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