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Article

[Need of new clinical criteria for the identification of genetic Lynch syndrome].

Acta medica portuguesa - 1 Jan 2000

Sousa Rita, Lage Pedro, Ferreira Sara, Claro Isabel, Francisco Inês, Filipe Bruno, Albuquerque Cristina, Suspiro Alexandra, Rodrigues Paula, Nobre-Leitão Carlos

Abstract excerpt

BACKGROUND: Surveillance programs in families with Hereditary Non-Polyposis Colorectal Cancer (HNPCC), which is an autossomal dominant disease, decrease colorectal carcinoma mortality. There are multiple clinical criteria for the identification of these families, mainly: the Amsterdam Criteria (ACI), the modified Amsterdam Criteria (ACII) and the Bethesda Guidelines (BG). AIMS: To correlate, in families with...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 18331697

Genes

MLH1
MSH2
MSH6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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