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Article

[Management of hereditary non-polyposis syndrome (Lynch syndrome)].

Harefuah - 1 Apr 2011

Kariv Revital, Goldberg Yael, Soler Irit, Rosner Gie, Half Elizabeth, Moshkowitz Menachem, Vilkin Alex, Levi Zohar, Niv Yaron

Abstract excerpt

Genetic background is suspected in about 20% of colorectal cancer (CRC) cases, in which either genetic polymorphisms or Mendelian heritable factors are involved. Currently known CRC syndromes include various polyposis syndromes (<1% of total CRC cases) and Lynch syndrome (LS), previously termed hereditary nonpolyposis colorectal cancer (HNPCC, comprises 3-5% of all CRC cases). LS is caused by dominantly inherited...

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Share to Colorectal Neoplasms, Hereditary Nonpolyposis
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Source

Identifiers

PMID: 22164924

Genes

MLH1
MSH2
MSH6
PMS2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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