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Article

Substitution of aspartic acid with glutamic acid increases the unfolding transition temperature of a protein.

Biochemical and biophysical research communications - 30 Jul 2004

Lee Duck Yeon, Kim Kyeong-Ae, Yu Yeon Gyu, Kim Key-Sun

Abstract excerpt

Proteins from thermophiles are more stable than those from mesophiles. Several factors have been suggested as causes for this greater stability, but no general rule has been found. The amino acid composition of thermophile proteins indicates that the content of polar amino acids such as Asn, Gln, Ser, and Thr is lower, and that of charged amino acids such as Arg, Glu, and Lys is higher than in mesophile proteins....

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Identifiers

PMID: 15240133
DOI: 10.1016/j.bbrc.2004.06.031

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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