Article
Increasing protein stability by improving beta-turns.
Proteins - 15 Nov 2009
Fu Hailong, Grimsley Gerald R, Razvi Abbas, Scholtz J Martin, Pace C Nick
Abstract excerpt
Our goal was to gain a better understanding of how protein stability can be increased by improving beta-turns. We studied 22 beta-turns in nine proteins with 66-370 residues by replacing other residues with proline and glycine and measuring the stability. These two residues are statistically preferred in some beta-turn positions. We studied: Cold shock protein B (CspB), Histidine-containing phosphocarrier...
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