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Article

Asymmetric substitution patterns in the two DNA strands of bacteria.

Molecular biology and evolution - 1 May 1996

Lobry J R

Abstract excerpt

Analyses of the genomes of three prokaryotes, Escherichia coli, Bacillus subtilis, and Haemophilus influenzae, revealed a new type of genomic compartmentalization of base frequencies. There was a departure from intrastrand equifrequency between A and T or between C and G, showing that the substitution patterns of the two strands of DNA were asymmetric. The positions of the boundaries between these compartments...

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Identifiers

PMID: 8676740
DOI: 10.1093/oxfordjournals.molbev.a025626

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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