Article
Distinct MHC class I and II alleles are associated with hepatitis C viral clearance, originating from a single source.
Hepatology (Baltimore, Md.) - 1 Jul 2004
McKiernan Susan M, Hagan Richard, Curry Michael, McDonald George S A, Kelly Alan, Nolan Niamh, Walsh Anne, Hegarty John, Lawlor Emer, Kelleher Dermot
Abstract excerpt
The role of cytotoxic T lymphocyte responses, restricted by human leukocyte antigen (HLA) class I alleles, is recognized as highly significant in the successful clearance of hepatitis C virus (HCV). The frequency of class I alleles in females inoculated with HCV genotype 1b from a single source w...
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