Article
Recovery of Na-glucose cotransport activity after renal ischemia is impaired in mice lacking vimentin.
American journal of physiology. Renal physiology - 1 Nov 2004
Runembert Isabelle, Couette Sylviane, Federici Pierre, Colucci-Guyon Emma, Babinet Charles, Briand Pascale, Friedlander Gérard, Terzi Fabiola
Abstract excerpt
Vimentin, an intermediate filament protein mainly expressed in mesenchyma-derived cells, is reexpressed in renal tubular epithelial cells under many pathological conditions, characterized by intense cell proliferation. Whether vimentin reexpression is only a marker of cell dedifferentiation or is instrumental in the maintenance of cell structure and/or function is still unknown. Here, we used vimentin knockout...
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