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Article

Insulin gene profile cycles with season of birth of future diabetic children and their relatives.

Journal of pediatric endocrinology & metabolism : JPEM - 1 May 2004

Mikulecký M, Minárik P, Michalková D

Abstract excerpt

BACKGROUND: HLA class II gene pattern and IA-2A antibody positivity, revealing selected risks for prediction of type 1 diabetes mellitus (DM1), were previously shown to be cycling roughly in parallel with seasonally fluctuating frequencies of births of future diabetic children. Is this also true for insulin genotyping? Is this also true for births of the healthy close relatives of children with DM1? PATIENTS AND...

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Identifiers

PMID: 15237706
DOI: 10.1515/jpem.2004.17.5.727

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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