Seasonal birth patterns in myositis subgroups suggest an etiologic role of early environmental exposures

Abstract excerpt

OBJECTIVE: To evaluate whether seasonal early environmental exposures might influence later development of autoimmune disease, by assessing distributions of birth dates in groups of patients with idiopathic inflammatory myopathies (IIMs). METHODS: We assessed birth patterns in groups of patients with juvenile-onset IIM (n = 307) and controls (n = 3,942) who were born between 1970 and 1999, and in groups of...

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