Article
Association of highly active antiretroviral therapy failure with chemokine receptor 5 wild type.
HIV medicine - 1 Jul 2004
Bogner J R, Lutz B, Klein H G, Pollerer C, Troendle U, Goebel F D
Abstract excerpt
OBJECTIVES: Approximately 10% of HIV-infected patients fail to respond properly to highly active antiretroviral therapy (HAART). Among other factors, genetic variants of chemokine receptors have been shown to modify the course and outcome of HIV infection. Our objective was to investigate whether a failure of virological response is associated with polymorphisms of the chemokine receptors or cofactors. METHODS: A...
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