Discordant response to antiretroviral therapy: HIV isolation, genotypic mutations, T-cell proliferation and cytokine production.

doi:10.1097/00002030-200209270-00004

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Discordant response to antiretroviral therapy: HIV isolation, genotypic mutations, T-cell proliferation and cytokine production.

AIDS (London, England) - 27 Sept 2002

D'Ettorre Gabriella, Forcina Gabriele, Andreotti Mauro, Sarmati Loredana, Palmisano Lucia, Galluzzo Clementina M, Nicastri Emanuele, Mastroianni Claudio M, Vullo Vincenzo, Vella Stefano, Andreoni Massimo

Abstract excerpt

OBJECTIVE: To study virologic and immunologic factors associated with discordant treatment response in HIV-infected patients receiving highly active antiretroviral therapy (HAART). DESIGN: Study participants included a total of 27 patients: (a) 10 discordant patients (mean CD4+ cell count, 396.1 x 10 cells/l; mean HIV-RNA, 5.4 log copies/ml); (b) seven responder patients (mean CD4+ cell count, 997.5 x 10...

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Discordant response to antiretroviral therapy: HIV isolation, genotypic mutations, T-cell proliferation and cytokine production.

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