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Mono and diterpene production in Escherichia coli.

Biotechnology and bioengineering - 20 Jul 2004

Reiling K Kinkead, Yoshikuni Yasuo, Martin Vincent J J, Newman Jack, Bohlmann Jörg, Keasling Jay D

Abstract excerpt

Mono- and diterpenoids are of great industrial and medical value as specialty chemicals and pharmaceuticals. Production of these compounds in microbial hosts, such as Escherichia coli, can be limited by intracellular levels of the polyprenyl diphosphate precursors, geranyl diphosphate (GPP), and geranylgeranyl diphosphate (GGPP). To alleviate this limitation, we constructed synthetic operons that express three...

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PMID: 15236249
DOI: 10.1002/bit.20128

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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