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Article

Combining genotype improvement and statistical media optimization for isoprenoid production in E. coli.

PloS one - 1 Jan 2013

Zhang Congqiang, Chen Xixian, Zou Ruiyang, Zhou Kang, Stephanopoulos Gregory, Too Heng-Phon

Abstract excerpt

Isoprenoids are a large and diverse class of compounds that includes many high value natural products and are thus in great demand. To meet the increasing demand for isoprenoid compounds, metabolic engineering of microbes has been used to produce isoprenoids in an economical and sustainable manner. To achieve high isoprenoid yields using this technology, the availability of metabolic precursors feeding the...

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PMID: 24124471
DOI: 10.1371/journal.pone.0075164
PMCID: PMC3790805

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PTS

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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