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Article

Role of the transmembrane domain of FXYD7 in structural and functional interactions with Na,K-ATPase.

The Journal of biological chemistry - 30 Dec 2005

Li Ciming, Crambert Gilles, Thuillard Delphine, Roy Sophie, Schaer Danièle, Geering Käthi

Abstract excerpt

Members of the FXYD family are tissue-specific regulators of the Na,K-ATPase. Here, we have investigated the contribution of amino acids in the transmembrane (TM) domain of FXYD7 to the interaction with Na,K-ATPase. Twenty amino acids of the TM domain were replaced individually by tryptophan, and combined mutations and alanine insertion mutants were constructed. Wild type and mutant FXYD7 were expressed in...

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Source

Identifiers

PMID: 16269407
DOI: 10.1074/jbc.M508451200

Genes

FXYD7

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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