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Article

Novel exomphalos genetic mouse model: the importance of accurate phenotypic classification.

Journal of pediatric surgery - 1 Oct 2013

Carnaghan Helen, Roberts Tom, Savery Dawn, Norris Francesca C, McCann Conor J, Copp Andrew J, Scambler Peter J, Lythgoe Mark F, Greene Nicholas D, Decoppi Paolo, Burns Alan J, Pierro Agustino, Eaton Simon

Abstract excerpt

BACKGROUND: Rodent models of abdominal wall defects (AWD) may provide insight into the pathophysiology of these conditions including gut dysfunction in gastroschisis, or pulmonary hypoplasia in exomphalos. Previously, a Scribble mutant mouse model (circletail) was reported to exhibit gastroschisis. We further characterise this AWD in Scribble knockout mice. METHOD: Homozygous Scrib knockout mice were obtained...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 24094954
DOI: 10.1016/j.jpedsurg.2013.04.010
PMCID: PMC4030649

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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