Article
Association of HTR2A T102C and A-1438G polymorphisms with susceptibility to major depressive disorder: a meta-analysis.
Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology - 1 Dec 2014
Zhao Xue, Sun Liang, Sun Ye-Huan, Ren Cizao, Chen Jian, Wu Zhen-Qiang, Jiang Yu-Hong, Lv Xiao-Ling
Abstract excerpt
Serotonin 2A receptor (HTR2A) gene was implicated to be associated with major depressive disorder (MDD) susceptibility due to its role of key neurotransmitter in many physiologic processes. A great number of related studies reported in different populations have emerged. The results of these studies, however, have been inconsistent and thereby definite conclusions are difficult to establish. With the cumulative...
Topics
- Depressive Disorder, Major
- Genetic Association Studies
- Genetic Predisposition to Disease
- Humans
- Polymorphism, Single Nucleotide
- Receptors, Serotonin, 5-HT3