Minireview: Developmental Regulation of Thyrotropin Receptor Gene Expression in the Fetal and Newborn Thyroid

Abstract excerpt

The TSH receptor plays a pivotal role in thyroid gland growth, function, and differentiation in the mature animal, but only recently has its role in the fetus and neonate been examined. Observational studies comparing the developmental regulation of TSH receptor gene expression, with thyroid morphology, and thyroid-specific gene expression in the rodent model, are reviewed in the context of older literature....

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