Article
Identification of variant ABC-transporter genes among Onchocerca volvulus collected from ivermectin-treated and untreated patients in Ghana, West Africa.
Annals of tropical medicine and parasitology - 1 Jun 2004
Ardelli B F, Prichard R K
Abstract excerpt
Treatment with ivermectin (IVM) is known to cause a loss of polymorphism at certain loci of the beta-tubulin, gamma-aminobutyric-acid-receptor, glutamate-gated-chloride-channel and ATP-binding-cassette (ABC) transporter genes of IVM-resistant Haemonchus contortus. The genetic variation of four ABC-transporter homologues from Onchocerca volvulus was therefore investigated, to determine if any change in genetic...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
