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Article

Reduced genetic variation of an Onchocerca volvulus ABC transporter gene following treatment with ivermectin.

Transactions of the Royal Society of Tropical Medicine and Hygiene - 1 Dec 2007

Ardelli B F, Prichard R K

Abstract excerpt

In some trichostrongyloid nematodes, the early stages of ivermectin (IVM) resistance have been characterized by a shift in allele frequency and reduced polymorphism at loci of P-glycoprotein genes, glutamate-gated chloride channel genes and gamma-aminobutyric acid receptor genes. Mass treatment with IVM is an integral component of the onchocerciasis control programmes. Genetic variation of an Onchocerca volvulus...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 17904599
DOI: 10.1016/j.trstmh.2005.03.019

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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