Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Translation termination factors function outside of translation: yeast eRF1 interacts with myosin light chain, Mlc1p, to effect cytokinesis.

Molecular microbiology - 1 Jul 2004

Valouev I A, Urakov V N, Kochneva-Pervukhova N V, Smirnov V N, Ter-Avanesyan M D

Abstract excerpt

The translation termination factor eRF1 recognizes stop codons at the A site of the ribosome and induces peptidyl-tRNA hydrolysis at the peptidyl transferase centre. Recent data show that, besides translation, yeast eRF1 is also involved in cell cycle regulation. To clarify the mechanisms of non-translational functions of eRF1, we performed a genetic screen for its novel partner proteins. This screen revealed the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cytokinesis
Share to Genes, Suppressor

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Myosin Light Chains

Share to Peptide Chain Termination, Translational

Share to Peptide Termination Factors

Share to Precipitin Tests

Share to Protein Interaction Mapping

Share to Suppression, Genetic

Source

Identifiers

PMID: 15228544
DOI: 10.1111/j.1365-2958.2004.04157.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Translation termination factors function outside of translation: yeast eRF1 interacts with myosin light chain, Mlc1p, to effect cytokinesis.PMID 15228544Read ↗

Molecular dissection of translation termination mechanism identifies two new critical regions in eRF1.Semantic proximity Read ↗

The C-terminus of eRF1 defines a functionally important domain for translation termination in Saccharomyces cerevisiae.Semantic proximity Read ↗

N-terminal region of Saccharomyces cerevisiae eRF3 is essential for the functioning of the eRF1/eRF3 complex beyond translation termination.Semantic proximity Read ↗

The Translation Termination Factor eRF3 Interacts Sequentially with eRF1 and ABCE1 on the RibosomeSemantic proximity Read ↗

The eIF4E-binding protein Eap1 has similar but independent roles in cell growth and gene expression with the cytoplasmic deadenylase Ccr4.Semantic proximity Read ↗

A novel mutant of the Sup35 protein of Saccharomyces cerevisiae defective in translation termination and in GTPase activity still supports cell viability.Semantic proximity Read ↗

The role of N-terminal domain of translational release factor eRF3 for the control of functionality and stability in S. cerevisiae.Semantic proximity Read ↗

Translation termination in Arabidopsis thaliana: characterisation of three versions of release factor 1.Semantic proximity Read ↗

N-terminal extension of Saccharomyces cerevisiae translation termination factor eRF3 influences the suppression efficiency of sup35 mutations.Semantic proximity Read ↗

Inactivation of NMD increases viability of sup45 nonsense mutants in Saccharomyces cerevisiae.Semantic proximity Read ↗

Eukaryotic release factor 1 phosphorylation by CK2 protein kinase is dynamic but has little effect on the efficiency of translation termination in Saccharomyces cerevisiae.Semantic proximity Read ↗

The DEAD-box RNA helicase Dbp5 functions in translation termination.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.