Article
Sequential genotyping within TDT families.
Mathematical medicine and biology : a journal of the IMA - 1 Jun 2004
Iles Mark M, Cannings Chris
Abstract excerpt
We demonstrate that, given a limited amount of genotyping resources, the power of a TDT study can be increased substantially by genotyping within families sequentially. By sequential genotyping we mean that one parent in a family should be typed and then the decision on whether to continue genotyping the family is based on this parent's genotype. If it is decided to continue genotyping then a further decision is...
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