Anterior pituitary thyrotropes are multifunctional cells.

doi:10.1152/ajpendo.00194.2004

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Article

Anterior pituitary thyrotropes are multifunctional cells.

American journal of physiology. Endocrinology and metabolism - 1 Dec 2004

Villalobos Carlos, Núñez Lucía, García-Sancho Javier

Abstract excerpt

Anterior pituitary (AP) contains some unorthodox multifunctional cells that store and secrete two different AP hormones (polyhormonal cells) and/or respond to several hypothalamic-releasing hormones (HRHs; multiresponsive cells). Multifunctional cells may be involved in paradoxical secretion (secretion of a given AP hormone evoked by a noncorresponding HRH) and transdifferentiation (phenotypic switch between...

Topics

Adrenocorticotropic Hormone
Animals
Basophils
Female
Growth Hormone
Hormones
Hypothalamus
Luteinizing Hormone
Male
Mice
Mice, Inbred BALB C
Phenotype
Pituitary Gland, Anterior
Prolactin
Receptors, Cell Surface
Sex Characteristics
Thyrotropin

Source

Open in PubMed

Identifiers

PMID: 15226100
DOI: 10.1152/ajpendo.00194.2004

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