Article
Multifunctional cells of mouse anterior pituitary reveal a striking sexual dimorphism.
The Journal of physiology - 15 Jun 2003
Nuñez Lucía, Villalobos Carlos, Senovilla Laura, García-Sancho Javier
Abstract excerpt
The existence of cells storing and secreting two different anterior pituitary (AP) hormones (polyhormonal cells) or responding to several hypothalamic releasing hormones (HRHs) (multiresponsive cells) has been reported previously. These multifunctional cells could be involved in paradoxical secretion (AP hormone secretion evoked by a non-corresponding HRH) and transdifferentiation (phenotypic switch between...
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